AGAP2

AGAP2
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauAGAP2, CENTG1, GGAP2, PIKE, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Dynodwyr allanolOMIM: 605476 HomoloGene: 86815 GeneCards: AGAP2
Patrwm RNA pattern


Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

116986

n/a

Ensembl

ENSG00000135439

n/a

UniProt

Q99490

n/a

RefSeq (mRNA)

NM_001122772
NM_014770

n/a

RefSeq (protein)

NP_001116244
NP_055585

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn AGAP2 yw AGAP2 a elwir hefyd yn ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q14.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AGAP2.

  • PIKE
  • GGAP2
  • CENTG1

Llyfryddiaeth

  • "AGAP2 regulates retrograde transport between early endosomes and the TGN. ". J Cell Sci. 2010. PMID 20551179.
  • "GGAP2/PIKE-a directly activates both the Akt and nuclear factor-kappaB pathways and promotes prostate cancer progression. ". Cancer Res. 2009. PMID 19176382.
  • "Phosphoinositide-3-Kinase Enhancers, PIKEs: Their Biological Functions and Roles in Cancer. ". Anticancer Res. 2016. PMID 26977005.
  • "The roles of PIKE in tumorigenesis. ". Acta Pharmacol Sin. 2013. PMID 23770988.
  • "Frequent heterogeneous missense mutations of GGAP2 in prostate cancer: implications for tumor biology, clonality and mutation analysis.". PLoS One. 2012. PMID 22389719.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ AGAP2 - Cronfa NCBI

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