ALOX5AP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2Q7R, 2Q7M
Dynodwyr
Cyfenwau	ALOX5AP, FLAP, arachidonate 5-lipoxygenase activating protein
Dynodwyr allanol	OMIM: 603700 HomoloGene: 1231 GeneCards: ALOX5AP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • glutathione transferase activity • protein N-terminus binding • leukotriene-C4 synthase activity • glutathione peroxidase activity • GO:0001948, GO:0016582 protein binding • arachidonic acid binding • GO:0010577 enzyme activator activity Cydrannau o'r gell • integral component of membrane • nuclear membrane • endoplasmic reticulum membrane • bilen • nuclear envelope • Reticwlwm endoplasmig • cnewyllyn cell Prosesau biolegol • cellular response to calcium ion • leukotriene metabolic process • GO:0048554 positive regulation of catalytic activity • protein homotrimerization • lipoxygenase pathway • leukotriene biosynthetic process • lipoxin metabolic process • cellular oxidant detoxification • lipoxin biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	241	n/a
Ensembl	n/a	n/a
UniProt	P20292	n/a
RefSeq (mRNA)	NM_001204406 NM_001629	n/a
RefSeq (protein)	NP_001191335 NP_001620	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ALOX5AP yw ALOX5AP a elwir hefyd yn Arachidonate 5-lipoxygenase activating protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 13, band 13q12.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ALOX5AP.

• FLAP

• "The arachidonate 5-lipoxygenase activating protein gene polymorphism is associated with the risk of scleroderma-related interstitial lung disease: a multicentre European Scleroderma Trials and Research group (EUSTAR) study. ". Rheumatology (Oxford). 2017. PMID 28160477.
• "The SG13S114 polymorphism of the ALOX5AP gene is associated with ischemic stroke in Europeans: a meta-analysis of 8062 subjects. ". Neurol Sci. 2017. PMID 28101761.
• "Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein. ". FASEB J. 2015. PMID 26289316.
• "A promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP gene is associated with decreased risk of ischemic stroke in two independent Chinese populations. ". PLoS One. 2015. PMID 25815512.
• "Association of ALOX5AP rs10507391/SG13S114 A>T polymorphism with cerebral infarction in the Chinese population: a meta-analysis study.". Int J Neurosci. 2015. PMID 25242267.