APBA1
Protein sy'n cael ei godio yn y corff dynol gan y genyn APBA1 yw APBA1 a elwir hefyd yn Amyloid beta precursor protein binding family A member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q21.12.[2]
Cyfystyron
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn APBA1.
- X11
- X11A
- LIN10
- MINT1
- D9S411E
- X11ALPHA
Llyfryddiaeth
- "Multisite tyrosine phosphorylation of the N-terminus of Mint1/X11α by Src kinase regulates the trafficking of amyloid precursor protein. ". J Neurochem. 2016. PMID 26865271.
- "The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice. ". J Biol Chem. 2003. PMID 12970358.
- "Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains. ". J Biol Chem. 2000. PMID 11010978.
- "Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. ". EMBO J. 1997. PMID 9321393.
- "NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.". J Biol Chem. 1990. PMID 1968060.
Cyfeiriadau
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