CBX2

CBX2
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauCBX2, CDCA6, M33, SRXY5, chromobox 2
Dynodwyr allanolOMIM: 602770 HomoloGene: 7256 GeneCards: CBX2
Patrwm RNA pattern


Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

84733

n/a

Ensembl

ENSG00000173894

n/a

UniProt

Q14781

n/a

RefSeq (mRNA)

NM_005189
NM_032647

n/a

RefSeq (protein)

NP_005180
NP_116036

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CBX2 yw CBX2 a elwir hefyd yn Chromobox 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q25.3.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CBX2.

  • M33
  • CDCA6
  • SRXY5

Llyfryddiaeth

  • "Genotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role. ". Br J Cancer. 2014. PMID 25225902.
  • "Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation. ". PLoS One. 2008. PMID 19107218.
  • "Phosphorylation of CBX2 controls its nucleosome-binding specificity. ". J Biochem. 2017. PMID 28992316.
  • "Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer. ". Clin Epigenetics. 2016. PMID 26877821.
  • "Genome-wide identification of CBX2 targets: insights in the human sex development network.". Mol Endocrinol. 2015. PMID 25569159.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ CBX2 - Cronfa NCBI

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