EXOSC5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2NN6
Dynodwyr
Cyfenwau	EXOSC5, RRP41B, RRP46, Rrp46p, hRrp46p, p12B, Exosome component 5, CABAC
Dynodwyr allanol	OMIM: 606492 HomoloGene: 5981 GeneCards: EXOSC5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • 3'-5'-exoribonuclease activity • exoribonuclease activity • GO:0001948, GO:0016582 protein binding • RNA binding Cydrannau o'r gell • cytoplasm • cytosol • exosome (RNase complex) • nuclear exosome (RNase complex) • cytoplasmic exosome (RNase complex) • nucleolus • cnewyllyn cell • nucleoplasm Prosesau biolegol • regulation of mRNA stability • nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' • rRNA 3'-end processing • rRNA catabolic process • DNA deamination • GO:0071049, GO:0071048, GO:0071033 nuclear mRNA surveillance • defense response to virus • exonucleolytic catabolism of deadenylated mRNA • U4 snRNA 3'-end processing • polyadenylation-dependent snoRNA 3'-end processing • RNA catabolic process • rRNA processing • RNA phosphodiester bond hydrolysis, exonucleolytic Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	56915	n/a
Ensembl	ENSG00000077348	n/a
UniProt	Q9NQT4	n/a
RefSeq (mRNA)	NM_020158	n/a
RefSeq (protein)	NP_064543	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn EXOSC5 yw EXOSC5 a elwir hefyd yn Exosome component 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19q13.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EXOSC5.

• "Induction of CML28-specific cytotoxic T cell responses using co-transfected dendritic cells with CML28 DNA vaccine and SOCS1 small interfering RNA expression vector. ". Biochem Biophys Res Commun. 2006. PMID 16815301.
• "Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA. ". Nat Struct Mol Biol. 2012. PMID 22407013.
• "Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene. ". Cancer Immunol Immunother. 2008. PMID 18157497.
• "CML28 is a broadly immunogenic antigen, which is overexpressed in tumor cells. ". Cancer Res. 2002. PMID 12359762.
• "Interaction of human genes WT1 and CML28 in leukemic cells.". J Huazhong Univ Sci Technolog Med Sci. 2013. PMID 23392705.