HHIP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2WFT, 2WFX, 2WG3, 2WG4, 3HO3, 3HO4, 3HO5
Dynodwyr
Cyfenwau	HHIP, HIP, hedgehog interacting protein
Dynodwyr allanol	OMIM: 606178 HomoloGene: 32469 GeneCards: HHIP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • zinc ion binding • metal ion binding • GO:0001948, GO:0016582 protein binding • catalytic activity • hedgehog family protein binding Cydrannau o'r gell • cytoplasm • bilen • cellbilen • integral component of plasma membrane • extracellular region • cell surface • ciliary membrane • cnewyllyn cell Prosesau biolegol • negative regulation of smoothened signaling pathway • regulation of fibroblast growth factor receptor signaling pathway • skeletal system morphogenesis • animal organ morphogenesis • neuroblast proliferation • smoothened signaling pathway • negative regulation of signal transduction • dorsal/ventral pattern formation • epithelial tube branching involved in lung morphogenesis • GO:0072468 signal transduction • negative regulation of apoptotic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	64399	n/a
Ensembl	ENSG00000164161	n/a
UniProt	Q96QV1	n/a
RefSeq (mRNA)	NM_022475	n/a
RefSeq (protein)	NP_071920	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HHIP yw HHIP a elwir hefyd yn Hedgehog interacting protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q31.21.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HHIP.

• HIP

• "The hedgehog antagonist HHIP as a favorable prognosticator in glioblastoma. ". Tumour Biol. 2016. PMID 26482617.
• "Epigenetic regulation of human hedgehog interacting protein in glioma cell lines and primary tumor samples. ". Tumour Biol. 2015. PMID 25416442.
• "Comparison of the role of HHIP SNPs in susceptibility to chronic obstructive pulmonary disease between Chinese Han and Mongolian populations. ". Gene. 2017. PMID 28939338.
• "Smoking status and gene susceptibility play important roles in the development of chronic obstructive pulmonary disease and lung function decline: A population-based prospective study. ". Medicine (Baltimore). 2017. PMID 28640141.
• "Endothelial microparticles carrying hedgehog-interacting protein induce continuous endothelial damage in the pathogenesis of acute graft-versus-host disease.". Am J Physiol Cell Physiol. 2016. PMID 27009877.