HTATSF1

HTATSF1
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauHTATSF1, TAT-SF1, TATSF1, dJ196E23.2, HIV-1 Tat specific factor 1
Dynodwyr allanolOMIM: 300346 HomoloGene: 40950 GeneCards: HTATSF1
Patrwm RNA pattern


Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001163280
NM_014500

n/a

RefSeq (protein)

NP_001156752
NP_055315

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn HTATSF1 yw HTATSF1 a elwir hefyd yn HIV-1 Tat specific factor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq26.3.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HTATSF1.

  • TATSF1
  • TAT-SF1
  • dJ196E23.2

Llyfryddiaeth

  • "Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs. ". PLoS One. 2009. PMID 19479034.
  • "DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation. ". Genes Dev. 2009. PMID 19952111.
  • "Impact of sustained RNAi-mediated suppression of cellular cofactor Tat-SF1 on HIV-1 replication in CD4+ T cells. ". Virol J. 2012. PMID 23153325.
  • "Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing. ". RNA. 2011. PMID 21282347.
  • "Soluble HIV-1 gp120 enhances HIV-1 replication in non-dividing CD4+ T cells, mediated via cell signaling and Tat cofactor overexpression.". AIDS. 2005. PMID 15905670.

Cyfeiriadau

  1. "Human PubMed Reference:".
  2. HTATSF1 - Cronfa NCBI

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