KCNA4

KCNA4
Dynodwyr
CyfenwauKCNA4, HBK4, HK1, HPCN2, HUKII, KCNA4L, KCNA8, KV1.4, PCN2, potassium voltage-gated channel subfamily A member 4, MCIDDS
Dynodwyr allanolOMIM: 176266 HomoloGene: 20514 GeneCards: KCNA4
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002233

n/a

RefSeq (protein)

NP_002224

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KCNA4 yw KCNA4 a elwir hefyd yn Potassium voltage-gated channel subfamily A member 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p14.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KCNA4.

  • HK1
  • HBK4
  • PCN2
  • HPCN2
  • HUKII
  • KCNA8
  • KV1.4
  • KCNA4L

Llyfryddiaeth

  • "Identification of an evolutionarily conserved extracellular threonine residue critical for surface expression and its potential coupling of adjacent voltage-sensing and gating domains in voltage-gated potassium channels. ". J Biol Chem. 2008. PMID 18640987.
  • "Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue. ". Mol Pharmacol. 2008. PMID 17959711.
  • "Episodic ataxia type 1 mutations in the KCNA1 gene impair the fast inactivation properties of the human potassium channels Kv1.4-1.1/Kvbeta1.1 and Kv1.4-1.1/Kvbeta1.2. ". Eur J Neurosci. 2006. PMID 17156368.
  • "N type rapid inactivation in human Kv1.4 channels: functional role of a putative C-terminal helix. ". Mol Membr Biol. 2005. PMID 16308273.
  • "Molecular determinants of intracellular pH modulation of human Kv1.4 N-type inactivation.". Mol Pharmacol. 2002. PMID 12065763.

Cyfeiriadau

  1. "Human PubMed Reference:".
  2. KCNA4 - Cronfa NCBI

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