LIMK2

LIMK2
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauLIMK2, LIM domain kinase 2
Dynodwyr allanolOMIM: 601988 HomoloGene: 55911 GeneCards: LIMK2
EC number2.7.11.1
Patrwm RNA pattern




Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

3985

n/a

Ensembl

ENSG00000182541

n/a

UniProt

P53671

n/a

RefSeq (mRNA)

NM_016733
NM_001031801
NM_005569

n/a

RefSeq (protein)

NP_001026971
NP_005560
NP_057952

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LIMK2 yw LIMK2 a elwir hefyd yn LIM domain kinase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 22, band 22q12.2.[2]

Llyfryddiaeth

  • "LIMK2 mediates resistance to chemotherapeutic drugs in neuroblastoma cells through regulation of drug-induced cell cycle arrest. ". PLoS One. 2013. PMID 23991158.
  • "Phosphorylation-dependent regulation of unique nuclear and nucleolar localization signals of LIM kinase 2 in endothelial cells. ". J Biol Chem. 2006. PMID 16820362.
  • "Cloning and characterization of the alternative promoter regions of the human LIMK2 gene responsible for alternative transcripts with tissue-specific expression. ". Gene. 1999. PMID 10452946.
  • "Subcellular localization and protein interaction of the human LIMK2 gene expressing alternative transcripts with tissue-specific regulation. ". Biochem Biophys Res Commun. 1996. PMID 8954941.
  • "Whole Exome Sequencing Identifies Rare Protein-Coding Variants in Behçet's Disease.". Arthritis Rheumatol. 2016. PMID 26662719.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ LIMK2 - Cronfa NCBI

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