NDC80

NDC80
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauNDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hskinetochore complex component, NDC80 kinetochore complex component
Dynodwyr allanolOMIM: 607272 HomoloGene: 38141 GeneCards: NDC80
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

10403

n/a

Ensembl

ENSG00000080986

n/a

UniProt

O14777

n/a

RefSeq (mRNA)

NM_006101

n/a

RefSeq (protein)

NP_006092

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NDC80 yw NDC80 a elwir hefyd yn Kinetochore protein NDC80 homolog a NDC80, kinetochore complex component (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18p11.32.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NDC80.

  • HEC
  • HEC1
  • TID3
  • KNTC2
  • HsHec1
  • hsNDC80

Llyfryddiaeth

  • "Multisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity. ". Mol Biol Cell. 2015. PMID 25808492.
  • "MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation. ". Bioessays. 2015. PMID 25557589.
  • "Mechanism of Ska Recruitment by Ndc80 Complexes to Kinetochores. ". Dev Cell. 2017. PMID 28535377.
  • "NDC80 promotes proliferation and metastasis of colon cancer cells. ". Genet Mol Res. 2016. PMID 27173328.
  • "The mitotic regulator Hec1 is a critical modulator of prostate cancer through the long non-coding RNA BX647187 in vitro.". Biosci Rep. 2015. PMID 26612002.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ NDC80 - Cronfa NCBI

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