RBFOX2
Protein sy'n cael ei godio yn y corff dynol gan y genyn RBFOX2 yw RBFOX2 a elwir hefyd yn RNA-binding protein fox-1 homolog 2 a RNA binding fox-1 homolog 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q12.3.[2]
Cyfystyron
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RBFOX2.
- RTA
- fxh
- FOX2
- RBM9
- Fox-2
- HNRBP2
- HRNBP2
- dJ106I20.3
Llyfryddiaeth
- "An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. ". Nat Struct Mol Biol. 2009. PMID 19136955.
- "RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes. ". Mol Cell. 2016. PMID 27211866.
- "Aberrant Splicing Induced by Dysregulated Rbfox2 Produces Enhanced Function of CaV1.2 Calcium Channel and Vascular Myogenic Tone in Hypertension. ". Hypertension. 2017. PMID 28993448.
- "Rbfox proteins regulate microRNA biogenesis by sequence-specific binding to their precursors and target downstream Dicer. ". Nucleic Acids Res. 2016. PMID 27001519.
- "RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues.". Mol Cell Biol. 2013. PMID 23149937.
Cyfeiriadau
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