RRAD

RRAD
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauRRAD, RAD, RAD1, REM3, Ras related glycolysis inhibitor and calcium channel regulator
Dynodwyr allanolOMIM: 179503 HomoloGene: 3071 GeneCards: RRAD
Patrwm RNA pattern


Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

6236

n/a

Ensembl

ENSG00000166592

n/a

UniProt

P55042

n/a

RefSeq (mRNA)

NM_004165
NM_001128850

n/a

RefSeq (protein)

NP_001122322
NP_004156

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RRAD yw RRAD a elwir hefyd yn GTP-binding protein RAD a RRAD, Ras related glycolysis inhibitor and calcium channel regulator (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16q22.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RRAD.

  • RAD
  • RAD1
  • REM3

Llyfryddiaeth

  • "Rad knockdown induces mitochondrial apoptosis in bortezomib resistant leukemia and lymphoma cells. ". Leuk Res. 2012. PMID 22658652.
  • "Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma. ". Cancer Lett. 2012. PMID 22487779.
  • "RRAD inhibits aerobic glycolysis, invasion, and migration and is associated with poor prognosis in hepatocellular carcinoma. ". Tumour Biol. 2016. PMID 26546438.
  • "Rad GTPase inhibits the NFκB pathway through interacting with RelA/p65 to impede its DNA binding and target gene transactivation. ". Cell Signal. 2014. PMID 24632303.
  • "Aberrant methylation of the Ras-related associated with diabetes gene in human primary esophageal cancer.". Anticancer Res. 2013. PMID 24222170.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ RRAD - Cronfa NCBI

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