SMG5

SMG5
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauSMG5, EST1B, LPTS-RP1, LPTSRP1, SMG-5, nonsense mediated mRNA decay factor, SMG5 nonsense mediated mRNA decay factor
Dynodwyr allanolOMIM: 610962 HomoloGene: 9095 GeneCards: SMG5
Patrwm RNA pattern


Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

23381

n/a

Ensembl

ENSG00000198952

n/a

UniProt

Q9UPR3

n/a

RefSeq (mRNA)

NM_015327
NM_001323614
NM_001323615
NM_001323616
NM_001323617

n/a

RefSeq (protein)

NP_001310543
NP_001310544
NP_001310545
NP_001310546
NP_056142

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SMG5 yw SMG5 a elwir hefyd yn SMG5, nonsense mediated mRNA decay factor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q22.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SMG5.

  • EST1B
  • SMG-5
  • LPTSRP1
  • LPTS-RP1

Llyfryddiaeth

  • "Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6. ". Nucleic Acids Res. 2014. PMID 25013172.
  • "SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. ". Mol Cell. 2005. PMID 15721257.
  • "MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA. ". BMC Mol Biol. 2016. PMID 27473591.
  • "SMG7 acts as a molecular link between mRNA surveillance and mRNA decay. ". Mol Cell. 2004. PMID 15546618.
  • "The host nonsense-mediated mRNA decay pathway restricts Mammalian RNA virus replication.". Cell Host Microbe. 2014. PMID 25211080.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ SMG5 - Cronfa NCBI

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