SPIN1

SPIN1
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauSPIN1, SPIN, TDRD24, spindlin 1
Dynodwyr allanolOMIM: 609936 HomoloGene: 55983 GeneCards: SPIN1
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

10927

n/a

Ensembl

ENSG00000106723

n/a

UniProt

Q9Y657

n/a

RefSeq (mRNA)

NM_006717

n/a

RefSeq (protein)

NP_006708

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SPIN1 yw SPIN1 a elwir hefyd yn Spindlin 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q22.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SPIN1.

  • SPIN
  • TDRD24

Llyfryddiaeth

  • "Expression, purification, crystallization and preliminary X-ray analysis of human spindlin1, an ovarian cancer-related protein. ". Protein Pept Lett. 2006. PMID 16472086.
  • "Suppression of SPIN1-mediated PI3K-Akt pathway by miR-489 increases chemosensitivity in breast cancer. ". J Pathol. 2016. PMID 27171498.
  • "The histone code reader SPIN1 controls RET signaling in liposarcoma. ". Oncotarget. 2015. PMID 25749382.
  • "Overexpression of spindlin1 induces metaphase arrest and chromosomal instability. ". J Cell Physiol. 2008. PMID 18543248.
  • "Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation.". J Biol Chem. 2007. PMID 17082182.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ SPIN1 - Cronfa NCBI

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