4-(4-Methylphenyl)-4-oxobutanoic acid
4-(4-Methylphenyl)-4-oxobutanoic acid
Names
Preferred IUPAC name
4-(4-Methylphenyl)-4-oxobutanoic acid
Other names
3-(4-Methylbenzoyl)propionic acid 3-(p -Toluoyl)propionic acid 4-(4-Methylphenyl)-4-oxobutyric acid
Identifiers
ChemSpider
ECHA InfoCard
100.118.705
EC Number
UNII
InChI=1S/C11H12O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h2-5H,6-7H2,1H3,(H,13,14)
Y Key: OEEUWZITKKSXAZ-UHFFFAOYSA-N
Y InChI=1/C11H12O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h2-5H,6-7H2,1H3,(H,13,14)
Key: OEEUWZITKKSXAZ-UHFFFAOYAH
Properties
C 11 H 12 O 3
Molar mass
192.214 g·mol−1
Appearance
White powder
Melting point
129 °C (264 °F; 402 K)
Insoluble
Hazards[1]
Occupational safety and health (OHS/OSH):
Main hazards
Flammable
GHS labelling :
Warning
H315 , H319 , H335
P261 , P264 , P271 , P280 , P302+P352 , P304+P340 , P305+P351+P338 , P312 , P332+P313 , P337+P313 , P362 , P403+P233 , P405 , P501
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
4-(4-Methylphenyl)-4-oxobutanoic acid is an organic carboxylic acid . The preparation of it is used for undergraduate teaching of organic chemistry synthesis.
Preparation
4-(4-Methylphenyl)-4-oxobutanoic acid can be prepared by a Friedel–Crafts reaction between toluene and succinic anhydride catalyzed by a Lewis acid such as aluminium chloride .[2]
References
^ "3-(4-Methylbenzoyl)propionic acid" . pubchem.ncbi.nlm.nih.gov .
^ Preparation of 4-(p-methylphenyl)-4-oxobutanoic acid, Li Cuijuan, Lv Mingquan, Han Shuying, Xu Tanfeng (College of Chemistry and Molecule Engineering, Peking University), College Chemistry, Vol 20. Period 2.