A. Thomas Look is Professor of Pediatrics at Harvard Medical School and Vice-Chair for Research, Pediatric Oncology, Dana–Farber Cancer Institute.[1] He is a pioneer in the use of zebrafish in cancer research and made major contributions to the understanding of leukemia and neuroblastoma biology and pathogenesis.
^Langenau, David M.; Traver, David; Ferrando, Adolfo A.; Kutok, Jeffery L.; Aster, Jon C.; Kanki, John P.; Lin, Shuo; Prochownik, Ed; Trede, Nikolaus S.; Zon, Leonard I.; Look, A. Thomas (7 February 2003). "Myc-Induced T Cell Leukemia in Transgenic Zebrafish". Science. 299 (5608): 887–890. Bibcode:2003Sci...299..887L. doi:10.1126/science.1080280. PMID12574629. S2CID38069481.
^Kentsis, Alex; Reed, Casie; Rice, Kim L; Sanda, Takaomi; Rodig, Scott J; Tholouli, Eleni; Christie, Amanda; Valk, Peter J M; Delwel, Ruud; Ngo, Vu; Kutok, Jeffery L; Dahlberg, Suzanne E; Moreau, Lisa A; Byers, Richard J; Christensen, James G; Woude, George Vande; Licht, Jonathan D; Kung, Andrew L; Staudt, Louis M; Look, A Thomas (10 June 2012). "Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia". Nature Medicine. 18 (7): 1118–1122. doi:10.1038/nm.2819. PMC3438345. PMID22683780.
^Gutierrez, Alejandro; Pan, Li; Groen, Richard W.J.; Baleydier, Frederic; Kentsis, Alex; Marineau, Jason; Grebliunaite, Ruta; Kozakewich, Elena; Reed, Casie; Pflumio, Francoise; Poglio, Sandrine; Uzan, Benjamin; Clemons, Paul; VerPlank, Lynn; An, Frank; Burbank, Jason; Norton, Stephanie; Tolliday, Nicola; Steen, Hanno; Weng, Andrew P.; Yuan, Huipin; Bradner, James E.; Mitsiades, Constantine; Look, A. Thomas; Aster, Jon C. (9 January 2014). "Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia". Journal of Clinical Investigation. 124 (2): 644–655. doi:10.1172/JCI65093. PMC3904599. PMID24401270.
^Khatib, Z. A.; Inaba, T.; Valentine, M.; Look, A. T. (15 September 1994). "Chromosomal localization and cDNA cloning of the human DBP and TEF genes". Genomics. 23 (2): 344–351. doi:10.1006/geno.1994.1510. PMID7835883.
^Inaba, T.; Inukai, T.; Yoshihara, T.; Seyschab, H.; Ashmun, R. A.; Canman, C. E.; Laken, S. J.; Kastan, M. B.; Look, A. T. (8 August 1996). "Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor". Nature. 382 (6591): 541–544. Bibcode:1996Natur.382..541I. doi:10.1038/382541a0. PMID8700228. S2CID4321391.
^O'Neil, Jennifer; Tchinda, Joelle; Gutierrez, Alejandro; Moreau, Lisa; Maser, Richard S.; Wong, Kwok-Kin; Li, Wei; McKenna, Keith; Liu, X. Shirley; Feng, Bin; Neuberg, Donna; Silverman, Lewis; DeAngelo, Daniel J.; Kutok, Jeffery L.; Rothstein, Rodney; DePinho, Ronald A.; Chin, Lynda; Lee, Charles; Look, A. Thomas (24 December 2007). "Alu elements mediate MYB gene tandem duplication in human T-ALL". Journal of Experimental Medicine. 204 (13): 3059–3066. doi:10.1084/jem.20071637. PMC2150982. PMID18070937.