Adaklu-Anyigbe District is a former district that was located in Volta Region, Ghana. Originally it was formerly part of the then-larger Ho District on 10 March 1989, until the southern part was split off to create Adaklu-Anyigbe District on 13 August 2004; thus the remaining part has been retained as Ho Municipal District. However, on 28 June 2012, it was split off into two new districts: Agotime-Ziope District (capital: Agortime-Kpetoe) and Adaklu District (capital: Adaklu Waya). The district assembly was located in the central part of Volta Region and had Agortime-Kpetoe as its capital town.