CGUST was originally established as Ming Chi College of Technology in 1983. In 1988, the Chang Gung Institute of Nursing was established as a two-year junior college program for nursing. A five-year program was established in 1991 and the institute was promoted to Chang Gung Institute of Technology. It also offered a two-year college program. In 2004, the institute offered a four-year college program. In August 2011 the name was changed to Chang Gung University of Science and Technology.