Ernst (1758–1784), married Christine Wilhelmina Henriette Sophia von Bardeleben (1765-1835).
Second marriage
When his first wife died in 1773, on 17 May 1775 he remarried with the French Countess Johanna Henriette de Bombelles (1751-1822), sister of Marc Marie, Marquis de Bombelles. She was born as daughter of Count François Henri de Bombelles (1681-1760), guardian of the Duke of Orleans, and his wife, Genevieve Charlotte de Bradins de la Moisiere (b. 1727). As her family didn't belong to the small circle of reigning of former reigning families, their marriage was treated as morganatic and upon marriage she received the title of Countess von Reichenberg. They had no children. She married again, to Louis Le Tellier de Souvre, Marquis de Louvois (d. 1785). They also didn't have children.[2]
Reign
Under Constantine, Hesse-Wanfried was in 1755 returned to Hesse-Rotenburg after the death of Christian of Hesse-Wanfried. Hesse-Rotenburg, which had been divided in 1648, was now again reunited and remained so until the Treaty of Lunéville in 1801.