Chemical compound produced by lichens
Diffractaic acid
Names
IUPAC name
4-(2,4-dimethoxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,6-dimethylbenzoic acid
[1]
Other names
Diffractic acid,
[1] Dirbizomic acid,
[1] Dirhizomic acid,
[1] NSC 5901
[2] ,NSC 685595
[2]
Identifiers
ChEMBL
ChemSpider
InChI=1S/C20H22O7/c1-9-8-14(11(3)17(21)15(9)19(22)23)27-20(24)16-10(2)7-13(25-5)12(4)18(16)26-6/h7-8,21H,1-6H3,(H,22,23)
Key: MIJKZXWOOXIEEU-UHFFFAOYSA-N
[2]
O=C(O)C1=C(O)C(C)=C(OC(C2=C(OC)C(C)=C(OC)C=C2C)=O)C=C1C
Properties
C 20 H 22 O 7
Molar mass
374.389 g·mol−1
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
Diffractaic acid is a β-orcinol depside with the molecular formula C20 H22 O7 , which is produced by lichens .[3] [1] [4] Diffractaic acid has cytotoxic , cytogenetic , oxidative , analgesic and antiviral effects.[4]
The foliose lichen species Punctelia diffractaica is named for the presence of this compound.[5]
References
^ a b c d e "Diffractaic acid" . Pubchem.ncbi.NLM.nih.gov .
^ a b c "Diffractaic Acid (CAS 436-32-8)" . www.caymanchem.com .
^ Sukumaran, Swapna Thacheril; Sugathan, Shiburaj; Abdulhameed, Sabu (28 November 2020). Plant Metabolites: Methods, Applications and Prospects . Springer Nature. p. 265. ISBN 978-981-15-5136-9 .
^ a b Demir, Leyla; Toğar, Başak; Türkez, Hasan; Sozio, Piera; Aslan, Ali; Stefano, Antonio Di (2015). "The investigation of cytogenetic and oxidative effects of diffractaic acid on human lymphocyte cultures" . Brazilian Archives of Biology and Technology . 58 : 75–81. doi :10.1590/S1516-8913201502752 . ISSN 1516-8913 .
^ Kurokawa, S. (1999). "Notes on Flavopunctelia and Punctelia (Parmeliaceae), with descriptions of four new species". Bulletin of the Botanical Garden of Toyama . 4 : 25–32.
Further reading
Sinha, Rajeshwar P.; Häder, h c Donat-P. (6 October 2020). Natural Bioactive Compounds: Technological Advancements . Academic Press. p. 257. ISBN 978-0-12-820659-1 .