Ensor-Keenan House is a historic home located at Columbia, South Carolina. It built about 1870, and is a 1+1⁄2-story, Italianate style frame dwelling. It features a central projecting pavilion with a steeply pitched hipped roof and full width front porch. It was the home of Dr. Joshua Fulton Ensor, second medical superintendent of the State Asylum (South Carolina State Hospital).[2][3]