Grigore Petrovich Grigoriu was born in 1941 in Căușeni, Moldova. In school, Grigore played in the theater, practiced sports, including boxing. After graduation, he worked briefly as a porter at a railway.
Grigore Grigoriu began his artistic career in the Bălți National Theatre where he worked for six years, from 1959 to 1965.[3] Subsequently, he worked for five years in the TV-theater "Dialogue", after 1970 at the Republican Theater of the Young Spectator "Luceafarul".[4][5]
His first film role was Sawa Milchan in the 1966 film by Emil Loteanu, Red Glades. Grigore Grigoriu acted in Russia, Romania, Germany, Azerbaijan, and Ukraine, performed more than seventy roles in film and theater. The most famous of his roles is Loiko Zobar in the film Gypsies Are Found Near Heaven.
Grigore Grigoriu was killed in a car accident on December 20, 2003 near the Moldovan village of Palanca.[6][4] The actor is buried in the Central (Armenian) cemetery in Chișinău.[7]