Illustration of HLA-DR
HLA-DR6 (DR6) is a broad-antigen serotype that is further split into HLA-DR13 and HLA-DR14 antigen serotypes .
Serology
DR13, DR6 and other serotype recognition of some DRB1*13 and DRB1*14 alleles[1]
DRB1*
DR13
DR6
DR14
Sample
allele
%
%
%
size (N)
1301
81
14
1
3788
1302
74
17
2
3081
1303
69
10
2
948[2]
1304
87
127
1305
54
12
305[3]
1306
78
9
1307
>50
1
1308
45
55
9
1310
>75
5
DRB1*
DR14
DR6
DR13
N
1401
74
14
3
1942
1402
61
13
9
204
1403
72
12
2
37
1404
79
8
80[4]
1405
86
10
58
1406
37
15
22
117
1407
90
10
1408
25
4[5]
1410
>75
4
DR6 serological reactivity is relatively poor compared to other serological tests for DR antigens. Compare to DQ2 or DR7 .
Disease associations
DR13 and DR14 share a common association to myasthenia gravis .[6]
Allele groups
HLA-DRB1*13 and HLA-DRB1*14 encode serotypes of DR6.
References
Genetic loci DRB1 Serotypes Serotype of DRB3 Serotype of DRB4 Serotype of DRB5