The Fall River Railroad opened in phases in 1845–46. The section between Braintree and Randolph opened on August 28, 1846; it was extended to North Bridgewater by October, with through service to Fall River beginning in December 1846.[2][3][4]Randolph station was located between the villages of Randolph Centre and East Randolph.[5]
After the 1866 opening of the Dighton and Somerset Railroad, which passed directly through Randolph Centre with a station there, the existing Randolph station was renamed East Randolph.[6][7] On February 29, 1872, East Randolph separated from Randolph to become Holbrook.[8] The station was renamed Holbrook in March.[9] A new freight house was built in 1883.[10]
Holbrook station closed on June 30, 1959, when all remaining Old Colony Division service was discontinued. From 1984 to 1988, the Cape Cod & Hyannis Railroad stopped near the current station site.[11][12] Holbrook/Randolph station opened in September 1997.[13]