Štěpán's wife, Anička, with whom he fell in love in the last film, has died and left him as a single dad and a 50-year-old hypochondriac. His two close friends, Kendy and Karas, help him raise his son, Štěpán Jr. Kendy has decided he is done directing commercials; instead, he wants to try his hand at making a feature film. Štěpán works as the deputy head of the hospital ward and fights constantly with Vendulka, the new director. His attractive neighbour, Zuzana, a photographer, becomes his new love interest.
