The station's history traces back to 2008, when KGNS launched a third digital subchannel, affiliated with Telemundo. The station went on the air on July 12, 2011, as K10QK-D, owned by SagamoreHill Broadcasting and simulcasting KGNS-TV's third subchannel. It was sold to Gray Television on December 31, 2013, along with KGNS-TV. On October 4, 2018, the station's call sign was changed to KXNU-LD.
Newscasts
Newscasts on the station have existed since 2010, having branded as Telenoticias Laredo ever since then. In 2015, the newscasts switched to a set of Gray Television graphics and the "Telemundo News" theme from Cacharros Musik. On September 7, 2020, the newscasts switched to a newer set of Gray Television graphics and both "U-Phonix" and "Third Coast" from Stephen Arnold Music.