Pentedrone (also known as α-methylaminovalerophenone) is a stimulant of the cathinone class that has been sold as a designer drug and has been found since 2010 as an ingredient in a number of "bath salt" mixes sold as legal highs.[3][4][5][6][7][8][9]
Pentedrone has been linked to at least one death where it was combined with α-PVP and caused heart failure.[12]
Detection
A forensic standard of pentedrone is available, and the compound has been posted on the Forendex website of potential drugs of abuse.[13]
Legal status
On January 28, 2014, the DEA listed it, along with nine other synthetic cathinones, on the Schedule 1 with a temporary ban, effective February 27, 2014.[14]
Pentedrone is an Anlage II controlled drug in Germany.
As of October 2015 Pentedrone is a controlled substance in China.[15]
^Maheux CR, Copeland CR (January 2012). "Chemical analysis of two new designer drugs: buphedrone and pentedrone". Drug Testing and Analysis. 4 (1): 17–23. doi:10.1002/dta.385. PMID22113925. S2CID3250022.
^Poklis JL, Wolf CE, ElJordi OI, Liu K, Zhang S, Poklis A (January 2015). "Analysis of the first- and second-generation Raving Dragon Novelty Bath Salts containing methylone and pentedrone". Journal of Forensic Sciences. 60 Suppl 1 (11): S234–40. doi:10.1111/1556-4029.12629. PMID25470207. S2CID38295463.
^Hwang JY, Kim JS, Oh JH, Hong SI, Ma SX, Jung YH, Ko YH, Lee SY, Kim HC, Jang CG (January 2017). "The new stimulant designer compound pentedrone exhibits rewarding properties and affects dopaminergic activity". Addiction Biology. 22 (1): 117–128. doi:10.1111/adb.12299. PMID26290055. S2CID23807079.
^Sykutera M, Cychowska M, Bloch-Boguslawska E (May 2015). "A Fatal Case of Pentedrone and α-Pyrrolidinovalerophenone Poisoning". Journal of Analytical Toxicology. 39 (4): 324–9. doi:10.1093/jat/bkv011. PMID25737339.
^"Pentedrone". Southern Association of Forensic Scientists. Retrieved 8 September 2015.
^"关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.