He was one of the early adopters of conservation medicine.[8] The Society for Conservation Biology symposium in 2000, had focused on the "complex problem of emerging diseases".[8] He said in 2001 that there were "almost no examples of emerging wildlife diseases not driven by human environmental change...[a]nd few human emerging diseases don't include some domestic animal or wildlife component." His research has focused on investigating and predicting the impacts of new diseases on wildlife, livestock, and human populations, and he has been involved in research studies on epidemics such as the Nipah virus infection, the Australian Hendra outbreaks, the 2002–2004 SARS outbreak, Avian influenza, and the West Nile virus.[9]
Starting in 2014, Daszak was Principal Investigator of a six-year NIH project which was awarded to the EcoHealth Alliance and which focused on the emergence of novel zoonotic coronaviruses with a bat origin.[10] Among the aims of the project was to characterize the diversity and distribution of Severe acute respiratory syndrome–related coronavirus (SARSr-CoV) in bats, viruses with a significant risk of spillover, in southern China, based on data from spike protein sequences, infectious clone technology, infection experiments (both in vitro and in vivo), as well as analysis of receptor binding.[11] The six 1-year projects received $3.75 million in funding from the National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. National Institutes of Health agency.[10]
During times of large virus outbreaks Daszak has been invited to speak as an expert on epidemics involving diseases moving across the species barrier from animals to humans.[12][13][14] At the time of the Ebola outbreak in West Africa in 2014, Daszak said "Our research shows that new approaches to reducing emerging pandemic threats at the source would be more cost-effective than trying to mobilize a global response after a disease has emerged".[15]
In October 2019, when the U.S. federal government "quietly" ended the ten-year old program called PREDICT,[16] operated by United States Agency for International Development (USAID)'s emerging threats division,[17] Daszak said that, compared to the $5 billion the U.S. spent fighting Ebola in West Africa, PREDICT—which cost $250 million—was much less expensive. Daszak further stated, "PREDICT was an approach to heading off pandemics, instead of sitting there waiting for them to emerge, and then mobilizing."[17]
After the outbreak of the COVID-19 pandemic, Daszak noted in The New York Times that he and other disease ecologists had warned the WHO in 2018 that the next pandemic "would be caused by an unknown, novel pathogen that hadn't yet entered the human population", probably in a region with significant human-animal interaction.[23] The group included this hypothetical "Disease X" pathogen on a list of eight diseases which they recommended should be given highest priority in regard to research and development efforts, such as finding better diagnostic methods and developing vaccines.[24] He said, "As the world stands today on the edge of the pandemic precipice, it's worth taking a moment to consider whether Covid-19 is the disease our group was warning about."[23]
Prior to the pandemic, Daszak and EcoHealth Alliance were the only U.S.-based organization researching coronavirus evolution and transmission in China,[25] where they partnered with the Wuhan Institute of Virology, among others. On 1 April 2020, following the beginning of the COVID-19 pandemic in the United States, the USAID granted $2.26 million to the EcoHealth program for a six-month emergency extension of the program whose funding has expired in September 2019.[26][27] The University of California announced that the extension would support "detection of SARS-CoV-2 cases in Africa, Asia and the Middle East to inform the public health response" as well as investigation of "the animal source or sources of SARS-CoV-2 using data and samples collected over the past 10 years in Asia and Southeast Asia."[27]
An open letter co-authored by Daszak, signed by 27 scientists and published in The Lancet on 19 February 2020, stated: "We stand together to strongly condemn conspiracy theories suggesting that COVID-19 does not have a natural origin...and overwhelmingly conclude that this coronavirus originated in wildlife." It further warned that blaming Chinese researchers for the virus' origin jeopardised the fight against the disease.[28] In June 2021, The Lancet published an addendum in which Daszak listed his cooperation with researchers in China,[29] and he also recused himself from The Lancet's inquiry commission focused on COVID-19 origins.[30]
EcoHealth Alliance's project funding was "abruptly terminated" on 24 April 2020, by the National Institutes of Health. The move met with criticism,[19][31][32] including by a group of 77 Nobel Prize laureates who wrote to NIH Director Francis Collins that they "are gravely concerned"[33] by the decision and called the funding cut "counterintuitive, given the urgent need to better understand the virus that causes COVID-19 and identify drugs that will save lives."[34] An article on 8 May 2020 in the journal Science stated that the unusual 24 April decision to cut EcoHealth's funding had occurred shortly after "President Donald Trump alleged – without providing evidence – that the pandemic virus had escaped from a Chinese laboratory supported by the NIH grant, and vowed to end the funding."[35]
In May 2020, Daszak "said there was 'zero evidence' that the virus" was created in the Wuhan Institute of Virology during an appearance on "60 Minutes."[36]
Some critics, including journalist Nicholas Wade[39] and biologist Richard H. Ebright,[40] alleged that Daszak had a conflict of interest investigating the virus' origins in China. In 2021, a complaint was issued by a few Republican representatives asking for Daszak to be expelled from the National Academy of Medicine (NAM) based on conduct allegations. In 2022 this request was denied by the NAM, citing "no evidence" of the alleged breach in conduct.[41] The conduct probe by NAM to exonerate Daszak drew wider circles as the Republican minority staff of a bipartisan Senate committee led by Senator Richard Burr concluded "that the pandemic most likely began when the virus somehow escaped from WIV". Some NAM members called the probe into Daszak "frivolous and political", and wrote that such accusations against China are detrimental to pandemic preparedness, and hinder international collaboration to confront pandemics effectively.[42]
In May 2024, the United States Department of Health and Human Services suspended all federal funding for Daszak and the EHA, saying that he did not properly monitor research activities at the WIV and failed to report on their high-risk experiments. The department also began proceedings to permanently debar Daszak and the EHA from federal funding.[43]
^ abPeter Daszak profile, NIH grant 12891702, p. 43: "1999 Meritorious service award, CDC . . . 2002 Honored by the naming of a new species of centipede, Cryptops daszaki (J Nat Hist 36: 76–106) . . . 2013 Honored by the naming of a new parasite species, Isospora daszaki (Parasit. Res. 111: 1463–1466) . . . 2018 Member, National Academy of Medicine (NAM), USA"
^Ball, S. J.; Brown, M. A.; Snow, K. R. (2012). "A new species of Isospora (Apicomplexa: Eimeriidae) from the greenfinch Carduelis chloris (Passeriformes: Fringillidae)". Parasitology Research. 111 (4): 1463–1466. doi:10.1007/s00436-012-2980-0. PMID22706904. S2CID19233064.