Virologist and professor
Raul Andino is a virologist and professor in the Department of Microbiology and Immunology at the University of California, San Francisco.[2] He is noted for leading a team of researchers that developed the first new oral polio vaccine in 50 years.[3]
Early life and education
Raul Andino was born in 1957[1] in Argentina.[4] He completed his master's degree in Biology in 1980 and his Ph.D. in Chemistry in 1986, both at the University of Buenos Aires.[2]
Andino emigrated to the United States in the 1980s.[4] He then went on to work as a postdoctoral researcher first at the Whitehead Institute for Biomedical Research from 1986 to 1991, then at Rockefeller University in the lab of David Baltimore from 1991 to 1992.[2] He then joined the faculty of the University of California, San Francisco as an assistant professor.[2] He was promoted to associate professor in 1999, then full professor in 2003.[2]
Research
Raul Andino's research has long focused on poliovirus. Together with Andrew Macadam, Andino redesigned the polio vaccine so it can stop the virus from re-evolving.[5][6] His research has expanded to other enteroviruses and host defenses against other RNA viruses.[1] His group has also had a long-standing interest in RNA interference as an antiviral defense, and in the dynamics of viral evolution during infection and transmission.[1]
Notable publications
- Vignuzzi M, Stone JK... Andino R (2006). Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population. Nature. 439(7074): pgs. 344-348
- Gitlin L, Karelsky S, Andino R (2002). Short interfering RNA confers intracellular antiviral immunity in human cells. Nature. 418(6896): pgs. 430-434
- Crotty S, Camerson SE, Andino R (2001). RNA virus error catastrophe: direct molecular test using ribavirin. Proceedings of the National Academy of Sciences of the United States of America. 98(12): pgs. 6895-6900
- Gamarnik AV, Andino R (1998). Switch from translation to RNA replication in a positive-stranded RNA virus. Genes and Development. 12(15) pgs. 2293-2304
- Andino R, Rieckhof GE... Baltimore D (1993). Poliovirus RNA synthesis utilizes an RNP complex formed around the 5'-end of the viral RNA. EMBO Journal. 12(9): pgs. 3587-3598
References