The Threlkeld House is a historic house at 1301 North Boston Avenue in Russellville, Arkansas. It is a 1+1⁄2-story wood-frame structure, with a gable roof and weatherboard siding. At one corner, a recessed porch is supported by square posts, the corner one mounted on a pier of rusticated concrete blocks. The house was built in 1914, and is unusual as an early vernacular ("Plain Traditional") house in a neighborhood of later houses featuring other styles. The house was owned until 1995 by members of the Threlkeld family.[2]