Whalefall-1 RNA motif |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/2/27/Whalefall-1-RNA.svg/220px-Whalefall-1-RNA.svg.png) Consensus secondary structure of Whalefall-1 RNAs |
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Symbol | wf-1 |
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Rfam | RF01762 |
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RNA type | sRNA |
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Domain(s) | Whale fall metagenome |
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PDB structures | PDBe |
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The Whalefall-1 RNA motif (also called wf-1) refers to a conserved RNA structure that was discovered using bioinformatics.[1][2] Structurally, the motif consists of two stem-loops (see diagram), the second of which is often terminated by a CUUG tetraloop, which is an energetically favorable RNA sequence. Whalefall-1 RNAs are found only in DNA extracted from uncultivated bacteria found on whale fall, i.e., a whale carcass. As of 2010, Whalefall-1 RNAs have not been detected in any known, cultivated species of bacteria, and are thus one of several RNAs present in environmental samples.
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