عضو A از خانوادهٔ ۱۲ دومِـین لکتین نوع سی (انگلیسی: C-type lectin domain family 12 member A) که با نام CLL-1 هم شناخته میشود، یک پروتئین است که در انسان توسط ژن «CLEC12A» کُدگذاری میشود.[۵]
پروتئین حاصله یکی از اعضای خانوادهٔ بزرگ پروتئینهای حاوی لکتین نوع سی است که همگی در چسبندگی سلولی، پیامرسانی سلول-به-سلول، تجدید و بازیافت گلیکوپروتئین، التهاب و پاسخ ایمنی نقش دارند. این مولکول یک تنظیمکنندهٔ منفی برای عملکرد گرانولوسیتها و مونوسیتهاست.
van Rhenen A, van Dongen GA, Kelder A, Rombouts EJ, Feller N, Moshaver B, et al. (October 2007). "The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells". Blood. 110 (7): 2659–66. doi:10.1182/blood-2007-03-083048. PMID17609428.
Marshall AS, Willment JA, Pyz E, Dennehy KM, Reid DM, Dri P, et al. (August 2006). "Human MICL (CLEC12A) is differentially glycosylated and is down-regulated following cellular activation". European Journal of Immunology. 36 (8): 2159–69. doi:10.1002/eji.200535628. PMID16838277.
Ebner S, Sharon N, Ben-Tal N (October 2003). "Evolutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily". Proteins. 53 (1): 44–55. doi:10.1002/prot.10440. PMID12945048.
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