CLEC4M
عضو M از خانوادهٔ ۴ دومِـین لکتین نوع سی (انگلیسی: C-type lectin domain family 4 member M) که با نام CD299 هم شناخته میشود، یک پروتئین است که در انسان توسط ژن «CLEC4M» کُدگذاری میشود.[۵]
ژن یادشده، نوعی پروتئین تراپوستهای نوع ۲ به نام L-SIGN را کُدگذاری میکند که ۷۷٪ مشابهِ آنتیژن DC-SIGN است که قابلیت اتصال به گلیکوپروتئین gp120 اچآیوی را داراست.
منابع
- ↑ ۱٫۰ ۱٫۱ ۱٫۲ GRCh38: Ensembl release 89: ENSG00000104938 – Ensembl, May 2017
- ↑ ۲٫۰ ۲٫۱ ۲٫۲ GRCm38: Ensembl release 89: ENSMUSG00000031494 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Yokoyama-Kobayashi M, Yamaguchi T, Sekine S, Kato S (Apr 1999). "Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank". Gene. 228 (1–2): 161–7. doi:10.1016/S0378-1119(99)00004-9. PMID 10072769.
- مشارکتکنندگان ویکیپدیا. «CLEC4M». در دانشنامهٔ ویکیپدیای انگلیسی، بازبینیشده در ۲۵ دسامبر ۲۰۱۹.
برای مطالعهٔ بیشتر
- Baribaud F, Doms RW, Pöhlmann S (2006). "The role of DC-SIGN and DC-SIGNR in HIV and Ebola virus infection: can potential therapeutics block virus transmission and dissemination?". Expert Opin. Ther. Targets. 6 (4): 423–31. doi:10.1517/14728222.6.4.423. PMID 12223058.
- Becker Y (2004). "HIV-1 gp120 binding to dendritic cell receptors mobilize the virus to the lymph nodes, but the induced IL-4 synthesis by FcepsilonRI+ hematopoietic cells damages the adaptive immunity--a review, hypothesis, and implications". Virus Genes. 29 (1): 147–65. doi:10.1023/B:VIRU.0000032797.43537.d3. PMID 15215692.
- Lalor PF, Lai WK, Curbishley SM, et al. (2006). "Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo". World J. Gastroenterol. 12 (34): 5429–39. doi:10.3748/wjg.v12.i34.5429. PMC 4088223. PMID 17006978.
{{cite journal}}: نگهداری یادکرد:doi رایگان بینشان (رده) - Curtis BM, Scharnowske S, Watson AJ (1992). "Sequence and expression of a membrane-associated C-type lectin that exhibits CD4-independent binding of human immunodeficiency virus envelope glycoprotein gp120". Proc. Natl. Acad. Sci. U.S.A. 89 (17): 8356–60. doi:10.1073/pnas.89.17.8356. PMC 49917. PMID 1518869.
- Gattegno L, Ramdani A, Jouault T, et al. (1992). "Lectin-carbohydrate interactions and infectivity of human immunodeficiency virus type 1 (HIV-1)". AIDS Res. Hum. Retroviruses. 8 (1): 27–37. doi:10.1089/aid.1992.8.27. PMID 1736938.
- Soilleux EJ, Barten R, Trowsdale J (2000). "DC-SIGN; a related gene, DC-SIGNR; and CD23 form a cluster on 19p13". J. Immunol. 165 (6): 2937–42. doi:10.4049/jimmunol.165.6.2937. PMID 10975799.
- Pöhlmann S, Soilleux EJ, Baribaud F, et al. (2001). "DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans". Proc. Natl. Acad. Sci. U.S.A. 98 (5): 2670–5. doi:10.1073/pnas.051631398. PMC 30196. PMID 11226297.
- Bashirova AA, Geijtenbeek TB, van Duijnhoven GC, et al. (2001). "A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection". J. Exp. Med. 193 (6): 671–8. doi:10.1084/jem.193.6.671. PMC 2193415. PMID 11257134.
- Mummidi S, Catano G, Lam L, et al. (2001). "Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts". J. Biol. Chem. 276 (35): 33196–212. doi:10.1074/jbc.M009807200. PMID 11337487.
{{cite journal}}: نگهداری یادکرد:doi رایگان بینشان (رده) - Mitchell DA, Fadden AJ, Drickamer K (2001). "A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR. Subunit organization and binding to multivalent ligands". J. Biol. Chem. 276 (31): 28939–45. doi:10.1074/jbc.M104565200. PMID 11384997.
{{cite journal}}: نگهداری یادکرد:doi رایگان بینشان (رده) - Feinberg H, Mitchell DA, Drickamer K, Weis WI (2002). "Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR". Science. 294 (5549): 2163–6. doi:10.1126/science.1066371. PMID 11739956.
- Alvarez CP, Lasala F, Carrillo J, et al. (2002). "C-type lectins DC-SIGN and L-SIGN mediate cellular entry by Ebola virus in cis and in trans". J. Virol. 76 (13): 6841–4. doi:10.1128/JVI.76.13.6841-6844.2002. PMC 136246. PMID 12050398.
- Soilleux EJ, Morris LS, Rushbrook S, et al. (2002). "Expression of human immunodeficiency virus (HIV)-binding lectin DC-SIGNR: Consequences for HIV infection and immunity". Hum. Pathol. 33 (6): 652–9. doi:10.1053/hupa.2002.124036. PMID 12152166.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Lin G, Simmons G, Pöhlmann S, et al. (2003). "Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR". J. Virol. 77 (2): 1337–46. doi:10.1128/JVI.77.2.1337-1346.2003. PMC 140807. PMID 12502850.
- Pöhlmann S, Zhang J, Baribaud F, et al. (2003). "Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR". J. Virol. 77 (7): 4070–80. doi:10.1128/JVI.77.7.4070-4080.2003. PMC 150620. PMID 12634366.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Engering A, van Vliet SJ, Hebeda K, et al. (2004). "Dynamic populations of dendritic cell-specific ICAM-3 grabbing nonintegrin-positive immature dendritic cells and liver/lymph node-specific ICAM-3 grabbing nonintegrin-positive endothelial cells in the outer zones of the paracortex of human lymph nodes". Am. J. Pathol. 164 (5): 1587–95. doi:10.1016/S0002-9440(10)63717-0. PMC 1615649. PMID 15111305.
پیوند به بیرون
- CLEC4M protein, human در سرعنوانهای موضوعی پزشکی (MeSH) در کتابخانهٔ ملی پزشکی ایالات متحدهٔ آمریکا
- مکان ژن انسانی CLEC4M در مرورگر ژنومی UCSC.
- جزئیات ژن انسانی CLEC4M در مرورگر ژنومی UCSC.
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