PRDX2
پروکسیردوکسین ۲ (انگلیسی: Peroxiredoxin-2) یک پروتئین است که در انسان توسط ژن «PRDX2» کُدگذاری میشود.[۵][۶] این آنزیم یکی از اعضای خانوادهٔ آنزیمهای آنتیاکسیدانی پروکسیردوکسین است.
این پروتئین خواص محافظتکنندهٔ آنتیاکسیدانی دارد و احتمالاً در فعالیتهای ضد ویروسی لنفوسیت تی کشنده نیز مشارکت دارد. همچنین این پروتئین خواص تحریککنندگی در زمینهٔ زایش و تکثیر سلولی دارد و بههمین دلیل، ممکن است در بروز و پیشرفت سرطان نقش داشته باشد. چندین نسخهٔ رونویسی گوناگون از این ژن که ایزوفرمهای پروتئینی متفاوتی را میسازند، تاکنون کشف شدهاست.[۶]
منابع
- ↑ ۱٫۰ ۱٫۱ ۱٫۲ GRCh38: Ensembl release 89: ENSG00000167815 – Ensembl, May 2017
- ↑ ۲٫۰ ۲٫۱ ۲٫۲ GRCm38: Ensembl release 89: ENSMUSG00000005161 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Pahl P, Berger R, Hart I, Chae HZ, Rhee SG, Patterson D (Aug 1995). "Localization of TDPX1, a human homologue of the yeast thioredoxin-dependent peroxide reductase gene (TPX), to chromosome 13q12". Genomics. 26 (3): 602–6. doi:10.1016/0888-7543(95)80183-M. PMID 7607688.
- ↑ ۶٫۰ ۶٫۱ "Entrez Gene: PRDX2 peroxiredoxin 2".
- مشارکتکنندگان ویکیپدیا. «Peroxiredoxin 2». در دانشنامهٔ ویکیپدیای انگلیسی، بازبینیشده در ۲۶ آوریل ۲۰۱۸.
بیشتر بخوانید
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نگارخانه بانک داده پروتئین | |
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