ScRNA

scRNA, małe cytoplazmatyczne RNA (z ang. small cytoplasmic RNA) – niewielka, ewolucyjnie konserwowana cząsteczka RNA, należąca do rodziny cząsteczek RNA odpowiedzialnych za rozpoznawanie sygnału w komórce (ang. signal-recognition-particle-like RNA family). Jej obecność stwierdzono u wielu organimów eukariotycznych (m.in. u Homo sapiens, Schizosaccharomyces pombe), prokariotycznych (m.in. u Clostridium perfringens, Bacillus subtilis) oraz u organizmów z grupy Archaea[1]. Najlepiej scharakteryzowanym scRNA jest 7SL RNA związany z procesem przemieszczania błon oraz białek w retikulum endoplazmatycznym[2].

Przypisy

  1. ↑ K. Nakamura, E. Hashizume, T. Shibata, Y. Nakamura i inni. Small cytoplasmic RNA (scRNA) gene from Clostridium perfringens can replace the gene for the Bacillus subtilis scRNA in both growth and sporulation.. „Microbiology”. 141 (Pt 11), s. 2965-75, Nov 1995. PMID: 8535524. 
  2. ↑ F. Felici, G. Cesareni, JM. Hughes. The most abundant small cytoplasmic RNA of Saccharomyces cerevisiae has an important function required for normal cell growth.. „Mol Cell Biol”. 9 (8), s. 3260-8, Aug 1989. PMID: 2477683. 

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