Aprindin

Aprindin
Klinički podaci
Drugs.comInternacionalno ime leka
Identifikatori
CAS broj37640-71-4
ATC kodC01BB04 (WHO)
PubChemCID 2218
DrugBankDB01429 Зелена квачицаДа
ChemSpider2132 Зелена квачицаДа
UNII5Y48085P9Q Зелена квачицаДа
KEGGD02969 Зелена квачицаДа
ChEMBLCHEMBL1213033 Зелена квачицаДа

Aprindin je antiaritmički agens klase 1b.[1]

U jednoj studiji, on je odložio atrijalnu fibirlaciji duže od digoksina.[2]

Aprindin je efektivan pri oralnoj administraciji.[3]

Reference

  1. ^ Sato R; Hisatome I; Tanaka Y; et al. (1991). „Aprindine blocks the sodium current in guinea-pig ventricular myocytes”. Naunyn Schmiedebergs Arch. Pharmacol.. 344 (3): 331—6. PMID 1660104. 
  2. ^ Atarashi H, Inoue H, Fukunami M, Sugi K, Hamada C, Origasa H (2002). „Double-blind placebo-controlled trial of aprindine and digoxin for the prevention of symptomatic atrial fibrillation”. Circ. J.. 66 (6): 553—6. PMID 12074271. doi:10.1253/circj.66.553. Архивирано из оригинала 17. 10. 2013. г. Приступљено 10. 12. 2013. 
  3. ^ Reid PR, Greene HL, Varghese PJ (1977). „Suppression of refractory arrhythmias by aprindine in patients with the Wolff-Parkinson-White syndrome”. Br Heart J. 39 (12): 1353—60. PMC 483421 Слободан приступ. PMID 603737. doi:10.1136/hrt.39.12.1353. 

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