Bekaplermin

Bekaplermin
Klinički podaci
Prodajno imeRegranex, Regranex (OMJ Pharmaceuticals)
Drugs.comMonografija
Način primenetopikalno
Identifikatori
CAS broj165101-51-9 Зелена квачицаДа
ATC kodD03AX06 (WHO), A01AD08
DrugBankDB00102 Зелена квачицаДа
ChEMBLCHEMBL1201556 Зелена квачицаДа

Bekaplermin (Regranex) cikatrizant je koji je dostupa u obliku topikalnog gela. On se koristi za tretiranje dijabetičkih čireva stopala.[1] Bekaplermin se proizvodi primenom rekombinantne DNK tehnologije na kvascu Saccharomyces cerevisiae. Bekaplermin je homodimer čiji polipeptidni lanci su vezani disulfidnim vezama[2][3]

Reference

  1. ^ Nagai MK, Embil JM (2002). „Becaplermin: recombinant platelet derived growth factor, a new treatment for healing diabetic foot ulcers”. Expert Opin Biol Ther. 2 (2): 211—8. PMID 11849120. doi:10.1517/14712598.2.2.211. 
  2. ^ Knox, C.; Law, V.; Jewison, T.; Liu, P.; Ly, S.; Frolkis, A.; Pon, A.; Banco, K.; Mak, C.; Neveu, V.; Djoumbou, Y.; Eisner, R.; Guo, A. C.; Wishart, D. S. (2011). „DrugBank 3.0: A comprehensive resource for 'Omics' research on drugs”. Nucleic Acids Research. 39 (Database issue): D1035—D1041. PMC 3013709 Слободан приступ. PMID 21059682. doi:10.1093/nar/gkq1126. 
  3. ^ Wishart, David S.; Knox, Craig; Guo, An Chi; Cheng, Dean; Shrivastava, Savita; Tzur, Dan; Gautam, Bijaya; Hassanali, Murtaza (2008). „DrugBank: A knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Research. 36 (Database issue): D901—D906. PMC 2238889 Слободан приступ. PMID 18048412. doi:10.1093/nar/gkm958. 

Literatura

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