PSB-10

PSB-10
Identifikatori
ATC kodnone
SinonimiPSB-10

PSB-10 je lek koji deluje kao selektivan inverzni agonist[1] za adenozinski A3 receptor, sa visokom selektivnošću u odnosu na druga tri tipa adenozinskih receptora. Pokazano je da proizvodi antiinflamatorne efekte u životinjskim studijama.[2][3]

Reference

  1. ^ Hallmen C, Wiese M (2006). „Molecular dynamics simulation of the human adenosine A3 receptor: agonist induced conformational changes of Trp243”. Journal of Computer-aided Molecular Design. 20 (10-11): 673—84. PMID 17124628. doi:10.1007/s10822-006-9088-5. 
  2. ^ Bilkei-Gorzo A, Abo-Salem OM, Hayallah AM, Michel K, Müller CE, Zimmer A (2008). „Adenosine receptor subtype-selective antagonists in inflammation and hyperalgesia”. Naunyn-Schmiedeberg's Archives of Pharmacology. 377 (1): 65—76. PMID 18188542. doi:10.1007/s00210-007-0252-9. 
  3. ^ Müller CE (2003). „Medicinal chemistry of adenosine A3 receptor ligands”. Current Topics in Medicinal Chemistry. 3 (4): 445—62. PMID 12570761. doi:10.2174/1568026033392174. Архивирано из оригинала 14. 04. 2013. г. Приступљено 09. 10. 2018. 

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