Talnetant

Talnetant
Identifikatori
CAS broj174636-32-9 Зелена квачицаДа
ATC kodnone
PubChemCID 133090

Talnetant (SB-223,412) je antagonist neurokininskog 3 receptora koji je razvio GlaksoSmitKlajn. Talnetant se ispituje za nekoliko različitih funkcija, primarna od kojih je upalna bolest creva. Druge indikacija je potencijalna antipsihotička primena u lečenju šizofrenije.[1][2][3]

Vidi još

Референце

  1. ^ Evangelista, S. (јул 2005). „Talnetant GlaxoSmithKline”. Current Opinion on Investigational Drugs. 6 (7): 717—21. PMID 16044668. 
  2. ^ Houghton LA, Cremonini F, Camilleri M, Busciglio I, Fell C, Cox V, Alpers DH, Dewit OE, Dukes GE, Gray E, Lea R, Zinsmeister AR, Whorwell PJ (септембар 2007). „Effect of the NK(3) receptor antagonist, talnetant, on rectal sensory function and compliance in healthy humans”. Neurogastroenterology and Motility. 19 (9): 732—43. PMID 17727393. 
  3. ^ Dawson LA, Cato KJ, Scott C, Watson JM, Wood MD, Foxton R, de la Flor R, Jones GA, Kew JN, Cluderay JE, Southam E, Murkitt GS, Gartlon J, Pemberton DJ, Jones DN, Davies CH, Hagan J (јун 2008). „In Vitro and In Vivo Characterization of the Non-peptide NK(3) Receptor Antagonist SB-223412 (Talnetant): Potential Therapeutic Utility in the Treatment of Schizophrenia”. Neuropsychopharmacology. 33 (7): 1642—52. PMID 17728699. 

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