Akoupé Department was created in 2005 as a second-level subdivision via a split-off from Adzopé Department.[4] At its creation, it was part of Agnéby Region.
In 2011, districts were introduced as new first-level subdivisions of Ivory Coast. At the same time, regions were reorganised and became second-level subdivisions and all departments were converted into third-level subdivisions. At this time, Akoupé Department became part of La Mé Region in Lagunes District.