Chambersville was named for Elisha Chambers, who relocated to the area from North Carolina in 1847. He received a land grant from Peter's Colony for 320 acres (130 ha) of land along the east fork of the Trinity River in 1850. Three years later, he gave land to build a church and cemetery. A post office was established at Chambersville in 1894 and remained in operation until 1903, with Jacob Bryan serving as postmaster. In 1903, mail was routed to McKinney. Its population was 40 from the 1950s through 2000.[2]
On April 22, 1968, an F1 tornado struck Chambersville.[3][4]
