Katehin

Katehin
Chemical structure of (+)-Catechin
Nazivi
IUPAC naziv
(2R,3S)-2-(3,4-dihidroksifenil)-3,4-dihidro-2H-hromen-3,5,7-triol
Drugi nazivi
Cianidanol
(+)-katehin
D-katehin
Katehinska kiselina
Cianidol
Dekscianidanol
(2R,3S)-Katehin
2,3-trans-katehin
3,3',4',5,7–flavanpentol
Identifikacija
3D model (Jmol)
ChEBI
ChemSpider
ECHA InfoCard 100.005.297
UNII
  • Oc1ccc(cc1O)[C@H]3Oc2cc(O)cc(O)c2C[C@@H]3O
Svojstva
C15H14O6
Molarna masa 290,27 g·mol−1
Agregatno stanje Colorless solid
Tačka topljenja 175 °C (347 °F; 448 K)
λmax 276 nm
Hiralna rotacija [α]D +14.0°
Opasnosti
Opasnost u toku rada Mutagen za somatske ćelije sisara, bakterija i kvasca
Bezbednost prilikom rukovanja sciencelab AppliChem
R-oznake R36/37/38
S-oznake S26-S36
Letalna doza ili koncentracija (LD, LC):
LD50 (LD50)
 (+)-katehin: 10,000 mg/kg kod pacova (RTECS)
10,000 mg/kg kod miševa
3,890 mg/kg kod pacova (drugi izvori)
Farmakologija
Oralno
Farmakokinetika:
Urines
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Зелена квачицаДа verifikuj (šta je Зелена квачицаДаRed КрстићНе ?)
Reference infokutije

Katehin je flavan-3-ol, tip prirodnog fenola i antioksidans. On je biljni sekundarni metabolit iz grupe flavan-3-ola (ili jednostavno flavanola). Često se smatra da on pripada familiji flavonoida.

Ime katehinske hemijske familije je izvedeno iz katehu, što je sok ili ekstrakt Mimosa catechu (Acacia catechu L.f)[3]

Reference

  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ Zheng LT, Ryu GM, Kwon BM, Lee WH, Suk K (2008). „Anti-inflammatory effects of catechols in lipopolysaccharide-stimulated microglia cells: inhibition of microglial neurotoxicity”. Eur. J. Pharmacol.. 588 (1): 106—13. PMID 18499097. doi:10.1016/j.ejphar.2008.04.035. 

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