NPR2
| Natriuretski peptidni receptor B/guanilat ciklaza B (atrionatriuretski peptidni receptor B) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | NPR2; AMDM; ANPRB; ANPb; GUC2B; GUCY2B; NPRB; NPRBi | ||||||||||
| Vanjski ID | OMIM: 108961 MGI: 97372 HomoloGene: 2970 GeneCards: NPR2 Gene | ||||||||||
| EC broj | 4.6.1.2 | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 4882 | 230103 | |||||||||
| Ensembl | ENSG00000159899 | ENSMUSG00000028469 | |||||||||
| UniProt | P20594 | Q6VVW5 | |||||||||
| RefSeq (mRNA) | NM_000907.2 | NM_173788.3 | |||||||||
| RefSeq (protein) | NP_003986.2 | NP_776149.1 | |||||||||
| Lokacija (UCSC) |
Chr 9: 35.79 - 35.81 Mb |
Chr 4: 43.63 - 43.65 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Natriuretski peptidni receptor B (atrionatriuretski peptidni receptor B, NPR2) je receptor atrijalnog natriuretskog peptida. Ovaj receptor je kod čoveka kodiran NPR1 genom.[1]
Reference
Literatura
- Fox AA; Collard CD; Shernan SK; et al. (2009). „Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.”. Anesthesiology. 110 (4): 738—47. PMC 2735337
. PMID 19326473. doi:10.1097/ALN.0b013e31819c7496. - Potthast R; Abbey-Hosch SE; Antos LK; et al. (2004). „Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B.”. J. Biol. Chem.. 279 (47): 48513—9. PMID 15371450. doi:10.1074/jbc.M408247200.
- Liew D; Schneider H; D'Agostino J; et al. (2004). „Utility of B-type natriuretic peptide as a screen for left ventricular dysfunction in patients with diabetes: response to Epshteyn et al.”. Diabetes Care. 27 (3): 848; author reply 848—9. PMID 14988324. doi:10.2337/diacare.27.3.848.
- Antos LK, Abbey-Hosch SE, Flora DR, Potter LR (2005). „ATP-independent activation of natriuretic peptide receptors.”. J. Biol. Chem.. 280 (29): 26928—32. PMID 15911610. doi:10.1074/jbc.M505648200.
- Poreba R; Poczatek K; Gać P; et al. (2009). „SNP rs198389 (T-381 C) polymorphism in the B-type natriuretic peptide gene promoter in patients with atherosclerotic renovascular hypertension.”. Pol. Arch. Med. Wewn.. 119 (4): 219—24. PMID 19413180.
- Koller KJ, Goeddel DV (1992). „Molecular biology of the natriuretic peptides and their receptors.”. Circulation. 86 (4): 1081—8. PMID 1327579.
- Fan D; Bryan PM; Antos LK; et al. (2005). „Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B: guanylyl cyclase-linked natriuretic peptide receptors do not internalize.”. Mol. Pharmacol.. 67 (1): 174—83. PMID 15459247. doi:10.1124/mol.104.002436.
- Pagel-Langenickel I, Buttgereit J, Bader M, Langenickel TH (2007). „Natriuretic peptide receptor B signaling in the cardiovascular system: protection from cardiac hypertrophy.”. J. Mol. Med.. 85 (8): 797—810. PMID 17429599. doi:10.1007/s00109-007-0183-4.
- Rahmutula D, Cui J, Chen S, Gardner DG (2004). „Transcriptional regulation of type B human natriuretic Peptide receptor gene promoter: dependence on Sp1.”. Hypertension. 44 (3): 283—8. PMID 15262909. doi:10.1161/01.HYP.0000136908.60317.92.
- Humphray SJ; Oliver K; Hunt AR; et al. (2004). „DNA sequence and analysis of human chromosome 9.”. Nature. 429 (6990): 369—74. PMC 2734081 . PMID 15164053. doi:10.1038/nature02465.
- Hume AN; Buttgereit J; Al-Awadhi AM; et al. (2009). „Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying acromesomelic dysplasia-type Maroteaux.”. Hum. Mol. Genet.. 18 (2): 267—77. PMC 2638773 . PMID 18945719. doi:10.1093/hmg/ddn354.
- Schulz S (2005). „C-type natriuretic peptide and guanylyl cyclase B receptor.”. Peptides. 26 (6): 1024—34. PMID 15911070. doi:10.1016/j.peptides.2004.08.027.
- Tsuji T, Kunieda T (2005). „A loss-of-function mutation in natriuretic peptide receptor 2 (Npr2) gene is responsible for disproportionate dwarfism in cn/cn mouse.”. J. Biol. Chem.. 280 (14): 14288—92. PMID 15722353. doi:10.1074/jbc.C500024200.
- Dickey DM, Yoder AR, Potter LR (2009). „A familial mutation renders atrial natriuretic Peptide resistant to proteolytic degradation.”. J. Biol. Chem.. 284 (29): 19196—202. PMC 2740543 . PMID 19458086. doi:10.1074/jbc.M109.010777.
- Nozohoor S; Nilsson J; Lührs C; et al. (2009). „B-type natriuretic peptide as a predictor of postoperative heart failure after aortic valve replacement.”. J. Cardiothorac. Vasc. Anesth.. 23 (2): 161—5. PMID 19167912. doi:10.1053/j.jvca.2008.11.006.
- Hachiya R; Ohashi Y; Kamei Y; et al. (2007). „Intact kinase homology domain of natriuretic peptide receptor-B is essential for skeletal development.”. J. Clin. Endocrinol. Metab.. 92 (10): 4009—14. PMID 17652215. doi:10.1210/jc.2007-1101.
- Gratacòs M; Costas J; de Cid R; et al. (2009). „Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.”. Am. J. Med. Genet. B Neuropsychiatr. Genet.. 150B (6): 808—16. PMID 19086053. doi:10.1002/ajmg.b.30902.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Bartels CF; Bükülmez H; Padayatti P; et al. (2004). „Mutations in the transmembrane natriuretic peptide receptor NPR-B impair skeletal growth and cause acromesomelic dysplasia, type Maroteaux.”. Am. J. Hum. Genet.. 75 (1): 27—34. PMC 1182004 . PMID 15146390. doi:10.1086/422013.
- van den Akker F (2001). „Structural insights into the ligand binding domains of membrane bound guanylyl cyclases and natriuretic peptide receptors.”. J. Mol. Biol.. 311 (5): 923—37. PMID 11556325. doi:10.1006/jmbi.2001.4922.
Vidi još
Spoljašnje veze
- NPR2+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
Content Disclaimer
Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.
- The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
- There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
- It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
- Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
- Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.