Tetramer

Primer podjedinica, ljudskog hemoglobina. Proteinske α i β podjedinice su obojene crveno i plavo.

Tetramer se sastoji od četiri podjedinice. Analogno svojstvo se naziva tetramerija. U hemiji se ovaj termin odnosi na molekul formiran od četiri monomera (na primer kobofenol A[1], molecule formiran od četiri stilbenoidna monomera).

U biohemiji, on ima slično značenje. To je biomolekul formiran od četiri podjedinice, koje mogu da budu identične (homotetramer), i.e. konkanavalin A[2] ili različite (heterotetramer), i.e. hemoglobin.[3] Hemoglobin ima 4 slične pidjednice, dok imunoglobulini imaju 2 veoma raličite podjedinice. Svaka od različitih podjedinica može da bude aktivna, npr. vezivanje biotina u avidinskim tetramerima, ili mogu da imaju zajedničko biološko svojstvo, kao što je alosterno vezivanje kiseonika u hemoglobinu.

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Tetramer на Викимедијиној остави.

Reference

  1. ^ Simultaneous determination of the contents of three stilbene oligomers in Caragana sinica collected in different seasons using an improved HPLC method. Shu Na; Zhou Hong; Hu Changqi, Shu, N.; Zhou, H.; Hu, C. (2006). „Simultaneous determination of the contents of three stilbene oligomers in Caragana sinica collected in different seasons using an improved HPLC method”. Biological & Pharmaceutical Bulletin. 29 (4): 608—612. PMID 16595888. doi:10.1248/bpb.29.608. ]
  2. ^ PDB: 3CNA​; Hardman KD, Ainsworth CF (1972). „Structure of concanavalin A at 2.4-A resolution”. Biochemistry. 11 (26): 4910—9. PMID 4638345. doi:10.1021/bi00776a006. 
  3. ^ Maton, Anthea; Hopkins, Jean; et al. (1993). Human Biology and Health. Englewood Cliffs, New Jersey, USA: Prentice Hall. ISBN 978-0-13-981176-0. 

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