Metopon

Metopon
Identifikatori
CAS broj143-52-2 Зелена квачицаДа
ATC kodnone
PubChemCID 5359353
ChemSpider4514264 Зелена квачицаДа

Metopon (5-metilhidromorfon) je opijatni analog, koji ima analgetsko dejstvo. On je metilisani derivat hidromorfona. Motopon je otriven 1948.[1]

Metopon se ponekad koristi u medicini. On ima duže vreme dejstva nego hidromorfon. Metopon je manje potentan, i njegova biodostupnost, mada veća od morfina, je još uvek niska, tako da metopon ima malobrojne prednosti u odnosu na druge analgetike.[2] On ima manje izraženu tendenciju da proizvede mučninu i hipoventilaciju u odnosu na morfin.[3]

Vidi još

Literatura

  1. ^ Eddy NB. Pharmacology of Metopon and other new analgesic opium derivatives. Annals of the New York Academy of Sciences. 51 (1): 51—58. 1948.  Недостаје или је празан параметар |title= (помоћ).
  2. ^ McLaughlin JP, Nowak D, Sebastian A, Schultz AG, Archer S, Bidlack JM. Metopon and two unique derivatives: affinity and selectivity for the multiple opioid receptors. European Journal of Pharmacology. 294 (1): 201—6. децембар 1995.  Недостаје или је празан параметар |title= (помоћ).
  3. ^ Daniel Lednicer. Central Analgetics. (1982), p145. ISBN 0-471-08314-3

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