NBUMP

NBUMP
Identifikatori
ATC kodnone
PubChemCID 64622

NBUMP je visoko selektivni parcijalni agonist 5-HT1A receptora (Ki = 0.1 nM; IA = 40%) sa arilpiperazinskom strukturom.[1] On je jedan od liganda sa najvećim afinitetom za 5-HT1A receptor.[2] On pokazuje 460- i 260-struku selektivnost za 5-HT1A u odnosu na α1-adrenergički i D2 receptore, respektivno.[2]

Reference

  1. ^ Roth, Bryan L. (2006). The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors). Totowa, NJ: Humana Press. ISBN 1-58829-568-0. 
  2. ^ а б Roth, Bryan L. (2006). The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors). Totowa, NJ: Humana Press. ISBN 1-58829-568-0. 

Literatura

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