Trazodon

Trazodon
Klinički podaci
Drugs.comMonografija
MedlinePlusa681038
Kategorija trudnoće
  • US: C (Mogući rizik)
Način primeneOralno
Pravni status
Pravni status
  • samo na recept
Identifikatori
CAS broj19794-93-5 Зелена квачицаДа
ATC kodN06AX05 (WHO)
PubChemCID 5533
IUPHAR/BPS213
DrugBankDB00656 Зелена квачицаДа
ChemSpider5332 Зелена квачицаДа
UNIIYBK48BXK30 Зелена квачицаДа
KEGGD08626 Зелена квачицаДа
ChEBICHEBI:9654 Зелена квачицаДа
ChEMBLCHEMBL621 Зелена квачицаДа

Trazodon (Desorel, Oleptro, Benefikat, Depraks, Desirel, Molipaksin, Tombran, Trazorel, Trialodin, Tritiko, i Mesirel) je antidepresiv iz klase serotoninskih antagonista i inhibitora preuzimanja (SARI). On je fenilpiperazinsko jedinjenje. Trazodon je isto tako anksiolitik i hipnotik.[1] Trazodon ima znatno manje izražene nuspojave koje su karakteristične za triciklične antidepresive.

Sinteza

Jedan od sintetičkih puteva je:[2][3]

Reference

  1. ^ Haria M, Fitton A, McTavish D (1994). „Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders”. Drugs Aging. 4 (4): 331—55. PMID 8019056. doi:10.2165/00002512-199404040-00006. 
  2. ^ Palazzo, G.; Silvestrini, B.; 1968, U.S. Patent 3,381,009.
  3. ^ B. Silvestrini, G. Palazzo, DE 164594 

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