GPR124
| G protein spregnuti receptor 124 | |||||||||||
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| Identifikatori | |||||||||||
| Simboli | GPR124; TEM5 | ||||||||||
| Vanjski ID | OMIM: 606823 MGI: 1925810 HomoloGene: 13112 IUPHAR: GPR124 GeneCards: GPR124 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 25960 | 78560 | |||||||||
| Ensembl | ENSG00000020181 | ENSMUSG00000031486 | |||||||||
| UniProt | Q96PE1 | Q91ZV8 | |||||||||
| RefSeq (mRNA) | NM_032777.9 | NM_054044.2 | |||||||||
| RefSeq (protein) | NP_116166.9 | NP_473385.2 | |||||||||
| Lokacija (UCSC) |
Chr 8: 37.64 - 37.7 Mb |
Chr 8: 28.2 - 28.23 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
G protein spregnuti receptor 124 je protein koji je kod ljudi kodiran GPR124 genom.[1][2][3]
Interakcije
GPR124 formira interakcije sa interact sa DLG1.[4]
Reference
- ^ Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, St Croix B (septembar 2001). „Cell surface tumor endothelial markers are conserved in mice and humans”. Cancer Res. 61 (18): 6649—55. PMID 11559528.
- ^ Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB (februar 2003). „There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini”. Biochem Biophys Res Commun. 301 (3): 725—34. PMID 12565841. doi:10.1016/S0006-291X(03)00026-3.
- ^ „Entrez Gene: GPR124 G protein-coupled receptor 124”.
- ^ Yamamoto, Yasunori; Irie Kenji; et al. (maj 2004). „Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein”. Oncogene. England. 23 (22): 3889—97. ISSN 0950-9232. PMID 15021905. doi:10.1038/sj.onc.1207495.
Literatura
- Nakajima D; Okazaki N; Yamakawa H; et al. (2003). „Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.”. DNA Res.. 9 (3): 99—106. PMID 12168954. doi:10.1093/dnares/9.3.99.
- Nagase T; Kikuno R; Ishikawa K; et al. (2000). „Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.”. DNA Res.. 7 (2): 143—50. PMID 10819331. doi:10.1093/dnares/7.2.143.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Ota T; Suzuki Y; Nishikawa T; et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs.”. Nat. Genet.. 36 (1): 40—5. PMID 14702039. doi:10.1038/ng1285.
- Yamamoto Y; Irie K; Asada M; et al. (2004). „Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.”. Oncogene. 23 (22): 3889—97. PMID 15021905. doi:10.1038/sj.onc.1207495.
- Bjarnadóttir TK; Fredriksson R; Höglund PJ; et al. (2005). „The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.”. Genomics. 84 (1): 23—33. PMID 15203201. doi:10.1016/j.ygeno.2003.12.004.
- Vallon M, Essler M (2006). „Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans.”. J. Biol. Chem.. 281 (45): 34179—88. PMID 16982628. doi:10.1074/jbc.M605291200.
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