GPR45
| G protein-spregnuti receptor 45 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | GPR45; PSP24; PSP24(ALPHA); PSP24A | ||||||||||
| Vanjski ID | OMIM: 604838 MGI: 2135882 HomoloGene: 5228 IUPHAR: GPR45 GeneCards: GPR45 Gene | ||||||||||
| |||||||||||
| Pregled RNK izražavanja | |||||||||||
 | |||||||||||
| podaci | |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 11250 | 93690 | |||||||||
| Ensembl | ENSG00000135973 | ENSMUSG00000041907 | |||||||||
| UniProt | Q9Y5Y3 | Q148B5 | |||||||||
| RefSeq (mRNA) | NM_007227 | NM_053107 | |||||||||
| RefSeq (protein) | NP_009158 | NP_444337 | |||||||||
| Lokacija (UCSC) |
Chr 2: 105.22 - 105.23 Mb |
Chr 1: 42.9 - 42.98 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
GPR45, G protein-spregnuti receptor 45, je protein koji je kod čoveka kodiran GPR45 genom.[1][2]
Ovaj gen ne sadrži introne. On kodira člana familije G protein-spregnutih receptora. Članovi te proteinske familije sadrže sedam transmembranskih domena i posreduju signalizacione procese u unutrašnjosti ćelije putem aktivacije heterotrimernih G proteina. Smatra se da ovaj protein deluje u centralnom nervnom sistemu.[2]
Literatura
- ^ Marchese A, Sawzdargo M, Nguyen T, Cheng R, Heng HH, Nowak T, Im DS, Lynch KR, George SR, O'dowd BF (1999). „Discovery of three novel orphan G-protein-coupled receptors”. Genomics. 56 (1): 12—21. PMID 10036181. doi:10.1006/geno.1998.5655.
- ^ а б „Entrez Gene: GPR45 G protein-coupled receptor 45”.
Dodatna literatura
- Kawasawa Y; Kume K; Nakade S; et al. (2000). „Brain-specific expression of novel G-protein-coupled receptors, with homologies to Xenopus PSP24 and human GPR45.”. Biochem. Biophys. Res. Commun.. 276 (3): 952—6. PMID 11027574. doi:10.1006/bbrc.2000.3569.
- Kawasawa Y, Kume K, Izumi T, Shimizu T (2000). „Mammalian PSP24s (alpha and beta isoforms) are not responsive to lysophosphatidic acid in mammalian expression systems.”. Biochem. Biophys. Res. Commun.. 276 (3): 957—64. PMID 11027575. doi:10.1006/bbrc.2000.3570.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899. - Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res.. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Hillier LW; Graves TA; Fulton RS; et al. (2005). „Generation and annotation of the DNA sequences of human chromosomes 2 and 4.”. Nature. 434 (7034): 724—31. PMID 15815621. doi:10.1038/nature03466.
Content Disclaimer
Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.
- The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
- There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
- It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
- Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
- Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.