GPR177
| G protein-coupled receptor 177 | |||||||
|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||
| Simboli | GPR177; MRP; C1orf139; FLJ23091; MGC131760; MGC14878; WLS | ||||||
| Vanjski ID | MGI: 1915401 HomoloGene: 11779 GeneCards: GPR177 Gene | ||||||
| |||||||
| Pregled RNK izražavanja | |||||||
 | |||||||
| podaci | |||||||
| Ortolozi | |||||||
| Vrsta | Čovek | Miš | |||||
| Entrez | 79971 | 68151 | |||||
| Ensembl | ENSG00000116729 | ENSMUSG00000028173 | |||||
| UniProt | Q5T9L3 | Q8CDZ6 | |||||
| RefSeq (mRNA) | NM_001002292 | NM_026582 | |||||
| RefSeq (protein) | NP_001002292 | NP_080858 | |||||
| Lokacija (UCSC) |
Chr 1: 68.34 - 68.47 Mb |
Chr 3: 159.78 - 159.87 Mb | |||||
| PubMed pretraga | [1] | [2] | |||||
G protein-spregnuti receptor 177 (GPR177), koji je poznat kao Wntless, je ljudski gen[1] koji kodira receptor za Wnt proteine u Wnt-sekretirajućim ćelijama.[2]
Za Wntless je nedavno bilo pokazano da je kargo za retromer kompleks[2]
Literatura
- ^ „Entrez Gene: GPR177 G protein-coupled receptor 177”.
- ^ а б Eaton S (2008). „Retromer retrieves wntless”. Dev. Cell.. 14 (1): 4—6. PMID 18194646. doi:10.1016/j.devcel.2007.12.014.
Dodatna literatura
- Gregory SG; Barlow KF; McLay KE; et al. (2006). „The DNA sequence and biological annotation of human chromosome 1.”. Nature. 441 (7091): 315—21. PMID 16710414. doi:10.1038/nature04727.
- Bänziger C; Soldini D; Schütt C; et al. (2006). „Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells.”. Cell. 125 (3): 509—22. PMID 16678095. doi:10.1016/j.cell.2006.02.049.
- Otsuki T; Ota T; Nishikawa T; et al. (2007). „Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”. DNA Res.. 12 (2): 117—26. PMID 16303743. doi:10.1093/dnares/12.2.117.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res.. 14 (10B): 2121—7. PMC 528928
. PMID 15489334. doi:10.1101/gr.2596504. - Ota T; Suzuki Y; Nishikawa T; et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs.”. Nat. Genet.. 36 (1): 40—5. PMID 14702039. doi:10.1038/ng1285.
- Clark HF; Gurney AL; Abaya E; et al. (2003). „The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”. Genome Res.. 13 (10): 2265—70. PMC 403697 . PMID 12975309. doi:10.1101/gr.1293003.
- Matsuda A; Suzuki Y; Honda G; et al. (2003). „Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.”. Oncogene. 22 (21): 3307—18. PMID 12761501. doi:10.1038/sj.onc.1206406.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A.. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Vidi još
- GPR177+receptor,+human на US National Library of Medicine Medical Subject Headings (MeSH)
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